CIT Elongation Tradeoffs Studies†

CIT Avoidance Guidelines and D-CIT Development

I]FP-CIT SPECT images

Aim The purpose of the current paper is to present a computational solution to accurately quantify a specific to a non-specific uptake ratio in [ 123 I]FP-CIT single photon emission computed tomography (SPECT) images and simultaneously measure the spatial dimensions of the basal ganglia, commonly known as basal nuclei. A statistical analysis based on a reference dataset selected by the user is ...

Automated quantification with BRASS reduces equivocal reporting of DaTSCAN (123I-FP-CIT) SPECT studies.

BACKGROUND ¹²³I-FP-CIT (DaTSCAN) SPECT studies of the nigrostriatal pathway are a valuable tool in the diagnosis of movement disorders. However some scans are reported as equivocal with potential adverse consequences. We investigated whether the use of quantification of tracer uptake within the striatum can be used to reduce the number of equivocal reports. MATERIAL AND METHODS BRASS software...

3D-OSEM and FP-CIT SPECT quantification: benefit for studies with a high radius of rotation?

OBJECTIVES Dopamine transporter imaging with single-photon emission computed tomography (SPECT) is a valuable tool for both clinical routine and research studies. Recently, it was found that the image quality could be improved by introduction of the three-dimensional ordered subset expectation maximization (3D-OSEM) reconstruction algorithm, which provides resolution recovery. The aim of this s...

Commentary: is CIT today's lobotomy?

Birthed in Memphis, Tennessee, in 1988, Crisis Intervention Teams (CITs) have had remarkable growth spurts with few, if any, developmental milestones to document their progress. Compton and colleagues investigated the evidence basis for CIT and found very little. They perhaps found even more than there actually is. There are contributions to CIT outcomes that are rooted in local variations in m...